We release anatomical fiducial (AFID) annotions on a subset of the Open Access Series of Imaging Studies. This subset consists of 30 subjects (age: 58.0 ± 17.9 years; range: 25-91; 17 female and 23 male) selected from the publicly available Open Access Series of Imaging Studies (OASIS-1) database and imaged at 3-T. The subjects were cognitively intact (Mini-Mental State Examination = 30), and the MRI scans were specifically chosen to be challenging (areas with more complex anatomy and asymmetries). A total of 3 AFIDs protocol applications (2,880 fiducials) were performed as part of the AFIDs-OASIS30 dataset. Neuroimaging data were provided by OASIS-1: Cross-Sectional: Principal Investigators: D. Marcus, R, Buckner, J, Csernansky J. Morris; P50 AG05681, P01 AG03991, P01 AG026276, R01 AG021910, P20 MH071616, U24 RR021382 IMPORTANT: Please note that by downloading and using imaging data in this dataset, you confirm that you have read and agreed to the Data Use Terms set by the Open Access Series of Imaging Studies outlined here: https://www.oasis-brains.org/#access