PDX_Decitabine_3DEpigenome

Code used to generate data and figures for Achinger-Kawecka et al. "Epigenetic therapy suppresses tumour growth by rewiring ER-mediated long-range chromatin interactions in ER+ endocrine-resistant breast cancer"

Organised into scripts for:

  1. Genome-wide Hi-C

For Hi-C saddle plots and compartment scores see: https://github.com/qianxidu/Replication_Timing_Du_et_al_2021/blob/main/Du_et_al_R_processing.Rmd

  1. Promoter Capture Hi-C
  2. RNA-seq (poly-A) including TE transcript / repeat analyses