zhangle0127/Global-Fund-Zhejiang-MDR-TB

Examine treatment outcomes, and predict the incidence of Tuberculosis

Global Fund on the Control of MDR-TB

The Global Fund to Fight AIDS, Tuberculosis and Malaria (or simply The Global Fund) is an international financing organization that aims to "[a]ttract and disburse additional resources to prevent and treat HIV and AIDS, tuberculosis and malaria."

Table of Contents

1. Data source
2. Methods
3. Reusable codes
4. Pulished paper

Data source

• Zhejiang Disease Prevention and Control Center

• Time Period: 2009-2013

• Population: Multidrug resistant tuberculosis patients (MDR-TB)

Methods

• Conducted a prospective observational cohort. MDR-TB patients were prescribed treatments by infectious disease specialists. Sociodemographic characteristics were obtained through a structured questionnaire.

• Examined treatment outcomes, literally cure rate.

• Assessed risk factors for poor treatment outcomes using a Cox proportional hazards model.

• Built a mathematical model to predict MDR-TB incidence in Zhejiang by 2050.

Reusable codes

• Clean Data

• Survival Analysis

• Cox proportional hazard Model

• Plot Figures and Create Tables

• Mathematical Model

Pulished paper

• Le Zhang, Qiong Meng, Songhua Chen, et al. Treatment outcomes of multidrug-resistant tuberculosis patients in Zhejiang, China, 2009-2013. Clinical Microbiology and Infection (IF: 5.3)

• Beibei Wu, Le Zhang(Co-first Author), et al. Drug-resistant tuberculosis in Zhejiang Province, China: an updated analysis of time trends, 1999–2013. (IF: 1.8)

• Ying Peng, Songhua Chen, Le Zhang, et al. Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013. (IF: 1.1)