association test
Closed this issue · 3 comments
SunYidan2021 commented
Hi Xiuwen,
I would like to ask how to understand the result of the association test. Is it necessary to calculate the Bonferroni-corrected p-values?
I also have some questions on convert alleles to Plink format. If I understand correctly, genotyped information is needed in this process. However, I would like to ask if it is possible to directly convert hlaAllele to Plink format.
Thank you in advance!
zhengxwen commented
Whether you need Bonferroni correction or not depends on your scientific question.
Try hlaAlleleToVCF()
to convert hlaAllele to PLINK.
hlaAlleleToVCF(hla, outfn, DS=TRUE, verbose=TRUE)
SunYidan2021 commented
Hi Xiuwen,
I try to use this function, however, I got an error.
Error in hlaAlleleToVCF() : could not find function "hlaAlleleToVCF"
zhengxwen commented
Update the version of the HIBAG package.
CHANGES IN VERSION 1.28.0
o new function `hlaAlleleToVCF()` for converting the imputed HLA classical alleles to a VCF file