REDUCE is an algorithm for optimal design of gene knock-out (KO) for the purpose of gene regulatory network (GRN) inference. Please refer to our manuscript entitled "Optimal design of gene knock-out experiments for gene regulatory network inference" for more details regarding the algorithm. The archive zip file provides MATLAB scripts for REDUCE.
Prerequisites: MATLAB 2014b (also tested on Octave 3.2.4), Python 2.7
Date of last modification: 08.10.2015
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Download & unzip the REDUCE.zip
Ud-Dean, SMM., and Gunawan, R. Optimal design of gene knock-out experiments for gene regulatory network inference. Bioinformatics 32 (6): 875-883 (2016). abstract
This work is supported by funding from Swiss National Science Foundation.