/mykrobe

Antibiotic resistance prediction in minutes

Primary LanguagePythonMIT LicenseMIT

Mykrobe

Antibiotic resistance prediction in minutes.

Currently supports Mycobacterium tuberculosis, Staphylococcus aureus, Shigella sonnei, Salmonella typhi and Salmonella enterica serotype Paratyphi B.

http://www.mykrobe.com

Documentation

Please see the mykrobe wiki for documentation. For S. typhi also see https://github.com/katholt/genotyphi

Quick start

Install:

  • bioconda - conda install -c bioconda mykrobe
  • from source - pip3 install . && mykrobe panels update_metadata && mykrobe panels update_species all
  • or using singularity or docker (see wiki for details)

Run on Mtb, making a JSON file of results:

mykrobe predict --sample my_sample_name \
  --species tb \
  --output out.json \
  --format json \
  --seq reads.fq.gz

Test reads can be obtained by running:

wget -O reads.fq.gz https://ndownloader.figshare.com/files/21059229