Analysis used in Damodaran et.al, Molecular Biology of the Cell , 2018
In the paper, we study the cellular response of cells of two different shapes (rectangle and circle) to the compressive force.
In this repository, we share the scripts used to analyse the transciption profile of rectangular and circular cells with and without compressive force. Our transcirptional analyis proved that there are cell shape dependent gene expression changes to compressive force.
We also present scripts used for specific image processing tasks.
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hcecratio.ijm was used to obtain the Heterochromatin to Euchromatin Ratio
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actinvsheight.ijm was used to calculate changes in actin intenisty along the height of the cell.
For more details visit our paper.