YosefLab/scone

Add wrapper for scran

Closed this issue · 4 comments

Add wrapper for scran

Closed by 38c19dc in develop

Must re-introduce @ckmah 's wrapper with additional automation / modified argument interface

ckmah commented

There is a case where the internal clustering step quickCluster may break if there are too few cells (less than default minimum threshold of 200). Similarly computeSumFactors has a minimum threshold of some sort as well. @mbcole If this isn't too urgent I would be happy to investigate.

I've added a non-clustering scran scaling function in 5c41e3d but I think we will ultimately want to pass arguments to a wrapper similar to your original. I've added a new issue for this: #84