Speed issues with large whitelist

[cnk113]

So I've been extensively using NextClone with our datasets, but something I noticed that was taking quite a while was the mapping with flexiplex. It would be great to somehow automate the discovery mode of flexiplex and the intersect it with the user provided whitelist?

Thanks

[ghar1821]

Hi there,

Thank you for using the software! Yes, Flexiplex run time do increases with the size of the whitelist. One thing you can do to speed NextClone up a bit is by increasing n_chunks, which then breaks up your samples into smaller sizes and increases the number of mapping jobs running in parallel.

But ultimately, yes we would like to build in the ability to reduce the whitelist size by intersecting it with flexiplex discovery mode.