Multi-omics Systems-Level Interactive Data Exploration (multiSLIDE)

User-driven concurrent heatmap visualization of large-scale multi-omics data

Our visualization tool multiSLIDE for hypothesis-driven, unbiased exploration of multi-omics data is described here:

Ghosh, S., Datta, A. & Choi, H. multiSLIDE is a web server for exploring connected elements of biological pathways in multi-omics data. Nat Commun 12, 2279 (2021). https://doi.org/10.1038/s41467-021-22650-x

Availability

multiSLIDE can be installed using the pre-built Docker image, the instructions are provided below.

Launch multiSLIDE locally using a Docker Image

The preferred way to run a local instance of multiSLIDE is using the pre-built Docker image available at Docker Hub, as follows:

Install Docker for Mac/Windows/Linux following the instructions here
Pull the multiSLIDE Docker image using the following command in Terminal(Mac) or Command Prompt(Windows) or the Linux Shell
```
$ docker pull soumitag/multislide:2.0
```

To launch multiSLIDE execute the following command:

$ docker run -d -p 8080:8080 soumitag/multislide:2.0

multiSLIDE should now be available at http://localhost:8080/multislide. Navigate to this link with your browser and start using multiSLIDE. Starting up the application might take a while, please take a sip of coffee and wait for a minute.

To stop multiSLIDE, first identify the name of the Docker container running multiSLIDE using:
```
$ docker ps
```
This command produces an output that looks like this:
```
CONTAINER ID  IMAGE			COMMAND 		  ...   PORTS 			NAMES
51a49fe8601a  soumitag/multislide:2.0   "/bin/sh -c \"/usr/lo…"   ...   0.0.0.0:8080->8080/tcp  youthful_wozniak
```
The last column of the output shows the container name. In this example it is "youthful_wozniak"

To stop this container use
```
$ docker stop youthful_wozniak
```

Overview

multiSLIDE is an open-source tool for query-driven visualization of quantitative single- or multi-omics data. Using pathways and networks as the basis for data linkage, multiSLIDE provides an interactive platform for querying the multi-omics data by genes, pathways, and intermolecular relationships.

Help

How to use multiSLIDE ?
- Videos tutorials demonstrating multiSLIDE's functionalities are available here