Consensus assembly problem
mikessh opened this issue · 0 comments
mikessh commented
Consensus assembly appears to be quite slow for 1000+ reads/MIG cases
Suggestion: re-implement consensus assembly in a MiGEC style with remapping
- Determine core seq, shift reads to fit core, align directly
- allow no more than 2 consequent errors
- Re-align dropped reads using K-mapper or some other aligner