Intersection of CMap and PFOCR extracted chemicals

Question

Intersection of CMap and PFOCR extracted chemicals

AlexanderPico opened this issue 4 years ago · 6 comments

In our shared NIA folder, this file has >6000 drugs annotated for repurposing: CMap_Repurposing_Hub.xlsx

Can you add a column to this table (or create a separate mapping table) based on the intersection of names?

There are no mappings from MeSH to BRD ID, unfortunately, so let's just see what we can get from a simple name match for now. I acknowledge that this will miss a lot of things.

Answer 1 · 2021-05-25T22:36:22.000Z

Here's a second list of drug names to attempt a quick intersection with:
https://www.dropbox.com/s/taia99vu2tah6cy/Full%20Library%20Gladstone%20%28with%20cpd%20names%29_20171106.xlsx?dl=0

Answer 2 · 2021-05-27T01:35:37.000Z

First batch:
https://www.dropbox.com/s/je6e3q513p5ql3p/CMap_Repurposing_Hub_PFOCR.xlsx?dl=0

Answer 3 · 2021-05-27T05:51:17.000Z

Second batch:
https://www.dropbox.com/s/ohu9k2on8yflydc/Full%20Library%20Gladstone%20%28with%20cpd%20names%29_20171106_PFOCR.xlsx?dl=0

Answer 4 · 2021-05-27T16:34:20.000Z

PFOCR overlaps:

1267 of 6798 CMap
1025 of 6912 Anke's library

Answer 5 · 2021-05-27T18:07:29.000Z

Code used:
https://github.com/wikipathways/pathway-figure-ocr/blob/master/notebooks/chemical_intersections.ipynb

Answer 6 · 2021-05-27T23:22:25.000Z

pfocr_id's for CMap: 13,575
pfocr_id's for Anke: 10,045