AlexandrovLab/SigProfilerExtractorR
An R wrapper for SigProfilerExtractor that allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
RBSD-2-Clause
Issues
- 2
- 1
Sigprofileextractor GRCh38 Exome Reference File Not Found Error After Installation
#14 opened by kevlumbus - 2
- 6
error in de_novo_fit_penalty
#7 opened by conormcguinness9016 - 1
error in de_novo_fit_penalty like in issue #7
#10 opened by frvirard - 2
No NAMESPACE file
#9 opened by pinunQ - 7
no cosmic decomposition for strand bias
#6 opened by frvirard - 1
- 1
- 1
Runtime error when using example data
#5 opened by waemm - 2
- 1
Decomposition function does not decomposite the de novo signatures to cosmic global signatures.
#2 opened by marshelma - 3