AntonioDeFalco/SCEVAN

some clarifications

aleednn opened this issue · 2 comments

  • How can I get the barcodes present in each subclone? (tsne_CNA graph)
  • tsne_CNA graph is done only on tumor cells?

Thank you!

Hi @aleednn,

  • How can I get the barcodes present in each subclone? (tsne_CNA graph)

The pipeline outputs a data.frame with this information as well, as shown in the vignette.

results <- pipelineCNA
Screenshot 2024-03-29 at 11 50 29

  • tsne_CNA graph is done only on tumor cells?

Yes, only on tumor cells.

Regards

Thank you @AntonioDeFalco for your reply.

i used:
results <- pipelineCNA(count_mtx, norm_cell = listNormCells, sample = "pt", par_cores = 25, SUBCLONES = TRUE, plotTree = TRUE)

but the value of confidential_normal in results is always "yes" for both tumor and non-tumor cells.

What could be the problem?

Regards.