AlexandrovLab/SigProfilerExtractor
SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
PythonBSD-2-Clause
Issues
- 0
Previously reported issue with PdfMerger
#262 opened by syparkmd - 0
- 4
- 3
Issue with PdfMerger
#259 opened by yingqizhang - 5
Running tool with custom CNV calls
#252 opened by kbrar4013 - 3
support MAF files?
#258 opened by wangzunq - 2
alexandrov ftp site is currently available?
#257 opened by a00101 - 5
cannot reindex on an axis with duplicate labels
#256 opened by jasmin774 - 1
Use of deprecated pandas
#255 opened by simonjuleseric2 - 1
- 4
- 1
Error while running the tool
#251 opened by itigupta2429 - 1
Could not read from remote repository.
#253 opened by Ryia-Illani - 1
- 1
Should the copy number segments be filtered before COPY NUMBER MATRIX GENERATION?
#249 opened by YingYa - 5
Singularity container creation
#233 opened by Katerina10-cloud - 14
CPU usage and GPU usage too little
#244 opened by xiaoyaojianghuzai - 2
user defined H_initials and W_initials
#248 opened by MariaCartolano - 2
Decomposing De Novo Signatures
#247 opened by ywhnet - 1
CPU usage and GPU usage too little, and parameters don't take effect
#243 opened by xiaoyaojianghuzai - 7
New issue with Indels
#236 opened by gafishbein - 3
- 1
- 4
IndexError occurred when processing directory /app/output: index out of range
#239 opened by xiaoyaojianghuzai - 1
- 5
sigProfilerExtractor for ID(INDELS)
#237 opened by shanimalik86 - 3
The difference between SBS96_De-Novo_Solution and COSMIC_SBS96_Decomposed_Solution.
#238 opened by shenhaizhongdechanrao - 1
Asking for SBS96 contexts in SigProfilerExtractor but receiving CH1000
#235 opened by emilysouthworth - 1
- 1
question about the SigProfilerExtractor
#232 opened by nan5895 - 1
Sample filtering before extraction
#231 opened by thisisliuyu - 3
ValueError: operands could not be broadcast together with shapes (83,0) (0,0)
#230 opened by dineshpeace - 1
Infinite loop
#228 opened by SukanyaPanja - 8
Custom opportunities matrix
#225 opened by gevro - 2
Issue with install
#229 opened by cutleraging - 2
AttributeError: 'NoneType' object has no attribute 'keys (decomposition.py error)
#227 opened by nan5895 - 1
- 5
SBS384 extraction problem
#221 opened by frvirard - 1
- 1
error because of new pandas version
#223 opened by sainadfensi - 1
- 5
interpretation for SBS 96D
#220 opened by sainadfensi - 0
- 1
calculate cosine similarity
#216 opened by me-nobody - 1
Cosine similarity for each COSMIC signature
#215 opened by nash5202 - 1
install own copy of genome
#213 opened by me-nobody - 3
[Errno 2] No such file or directory
#214 opened by KANGseungseok - 0
Alexandrov FTP server not responding
#212 opened by daanhazelaar - 5
UnicodeEncodeError: 'latin-1' codec can't encode characters in position 1-40: ordinal not in range(256)
#211 opened by anderdnavarro - 2
number of signatures in solution
#210 opened by bakeronit