crisprVerse/crisprDesign

DNA and RNA bulge off target DSB

frvcw opened this issue · 1 comments

frvcw commented

Hi

I want to consider the off target risk of DNA and gRNA bulges in the design of my protospacers. Is there a system in CrisprVerse that allows me to do it with my custom pakage genomes or should I rely on other programs e.g. Cas OFF finder?

Thank for your work

Jfortin1 commented

Hi @frvcw,

Unfortunately, our current aligners don't support DNA/RNA bulges